|
The Wohl–Ziegler reaction is a chemical reaction that involves the allylic or benzylic bromination of hydrocarbons using an ''N''-bromoimide and a radical initiator. : Best yields are achieved with ''N''-bromosuccinimide in carbon tetrachloride solvent. Several reviews have been published. In a typical setup a stoichiometric amount of ''N''-bromosuccinimide solution and a small quantity of initiator are added to a solution of the substrate in CCl4, and the reaction mixture is stirred and heated to the boiling point. Initiation of the reaction is indicated by more vigorous boiling; sometimes the heat source may need to be removed. Once all ''N''-bromosuccinimide (which is denser than the solvent) has been converted to succinimide (which floats on top) the reaction has finished. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Wohl–Ziegler bromination」の詳細全文を読む スポンサード リンク
|