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Wohl–Ziegler bromination
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Wohl–Ziegler bromination : ウィキペディア英語版
Wohl–Ziegler bromination

The Wohl–Ziegler reaction
is a chemical reaction that involves the allylic or benzylic bromination of hydrocarbons using an ''N''-bromoimide and a radical initiator.
:
Best yields are achieved with ''N''-bromosuccinimide in carbon tetrachloride solvent. Several reviews have been published.
In a typical setup a stoichiometric amount of ''N''-bromosuccinimide solution and a small quantity of initiator are added to a solution of the substrate in CCl4, and the reaction mixture is stirred and heated to the boiling point. Initiation of the reaction is indicated by more vigorous boiling; sometimes the heat source may need to be removed. Once all ''N''-bromosuccinimide (which is denser than the solvent) has been converted to succinimide (which floats on top) the reaction has finished.
==References==



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